Acciottolato di Pavia 

 

La maggior parte dei lavori elencati in questa sezione è costituita da collaborazioni con altri gruppi di ricerca. Questo spiega l'eterogeneità degli argomenti. In tutti questi studi la parte di spettrometria di massa è stata eseguita dal mio gruppo. Gli articoli in cui la spettrometria di massa è determinante o quelli provenienti dal mio laboratorio (non in collaborazione) sono evidenziati in rosso.

 

Salzano, AM, and Crescenzi, M. Mass spectrometry for protein identification and the study of post translational modifications. Ann Ist Super Sanita 41:443-450, 2005.

Bruno, T, De Nicola, F, Iezzi, S, Lecis, D, D'Angelo, C, Di Padova, M, Corbi, N, Dimiziani, L, Zannini, L, Jekimovs, C, Scarsella, M, Porrello, A, Chersi, A, Crescenzi, M, Leonetti, C, Khanna, KK, Soddu, S, Floridi, A, Passananti, C, Delia, D, and Fanciulli, M. Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint. Cancer Cell 10:473-486, 2006.

D'Errico, M, Parlanti, E, Teson, M, de Jesus, BM, Degan, P, Calcagnile, A, Jaruga, P, Bjoras, M, Crescenzi, M, Pedrini, AM, Egly, JM, Zambruno, G, Stefanini, M, Dizdaroglu, M, and Dogliotti, E. New functions of XPC in the protection of human skin cells from oxidative damage. Embo J 25:4305-4315, 2006.

Pajalunga, D, Mazzola, A, Salzano, AM, Biferi, MG, De Luca, G, and Crescenzi, M. Critical requirement for cell cycle inhibitors in sustaining nonproliferative states. J Cell Biol 176:807-818, 2007.

Lalle, M, Salzano, AM, Crescenzi, M, and Pozio, E. The Giardia duodenalis 14-3-3 protein is post-translationally modified by phosphorylation and polyglycylation of the C-terminal tail. J Biol Chem 281:5137-5148, 2006.

Pietraforte, D, Brambilla, G, Camerini, S, Scorza, G, Peri, L, Loizzo, A, Crescenzi, M, and Minetti, M. Formation of an adduct by clenbuterol, a beta-adrenoceptor agonist drug, and serum albumin in human saliva at the acidic pH of the stomach: Evidence for an aryl radical-based process. Free radical biology & medicine 45:124-135, 2008.

Mallozzi, C, Ceccarini, M, Camerini, S, Macchia, G, Crescenzi, M, Petrucci, TC, and Di Stasi, AM. Peroxynitrite induces tyrosine residue modifications in synaptophysin C-terminal domain, affecting its interaction with src. J Neurochem 111:859-869, 2009.

Di Girolamo, F, Ponzi, M, Crescenzi, M, Alessandroni, J, and Guadagni, F. A simple and effective method to analyze membrane proteins by SDS-PAGE and MALDI mass spectrometry. Anticancer Res 30:1121-1129, 2010.

Lalle, M, Bavassano, C, Fratini, F, Cecchetti, S, Boisguerin, P, Crescenzi, M, and Pozio, E. Involvement of 14-3-3 protein post-translational modifications in Giardia duodenalis encystation. Int J Parasitol 40:201-213, 2010.

Lanciotti, A, Brignone, MS, Camerini, S, Serafini, B, Macchia, G, Raggi, C, Molinari, P, Crescenzi, M, Musumeci, M, Sargiacomo, M, Aloisi, F, Petrucci, TC, and Ambrosini, E. MLC1 trafficking and membrane expression in astrocytes: role of caveolin-1 and phosphorylation. Neurobiol Dis 37:581-595, 2010.

Lalle, M, Camerini, S, Cecchetti, S, Fantauzzi, CB, Crescenzi, M, and Pozio, E. Giardia duodenalis 14-3-3 protein is polyglycylated by a tubulin tyrosine ligase-like member and deglycylated by two metallocarboxypeptidases. J Biol Chem 286:4471-4484, 2011.

Motta, M, Tatti, M, Martinelli, S, Camerini, S, Scarpa, S, Crescenzi, M, Tartaglia, M, and Salvioli, R. Efficient one-step chromatographic purification and functional characterization of recombinant human Saposin C. Protein Expr Purif 78:209-215, 2011.

Fratini, F, Macchia, G, Torreri, P, Matteucci, A, Salzano, AM, Crescenzi, M, Macioce, P, Petrucci, TC, and Ceccarini, M. Phosphorylation on threonine 11 of beta-dystrobrevin alters its interaction with kinesin heavy chain. The FEBS journal 279:4131-4144, 2012.

Fratini, F, Principe, S, Puopolo, M, Ladogana, A, Poleggi, A, Piscopo, P, Bruno, G, Castrechini, S, Pascone, R, Confaloni, A, Minghetti, L, Cardone, F, Pocchiari, M, and Crescenzi, M. Increased levels of acute-phase inflammatory proteins in plasma of patients with sporadic CJD. Neurology 79:1012-1018, 2012.

Giuliano, S, Iadarola, P, Leva, V, Montecucco, A, Camerini, S, Crescenzi, M, Salvini, R, and Bardoni, A. An insight into the abundant proteome of 46BR.1G1 fibroblasts deficient of DNA ligase I. Electrophoresis 33:307-315, 2012.

Lalle, M, Camerini, S, Cecchetti, S, Sayadi, A, Crescenzi, M, and Pozio, E. Interaction network of the 14-3-3 protein in the ancient protozoan parasite Giardia duodenalis. J Proteome Res 11:2666-2683, 2012.

Leva, V, Giuliano, S, Bardoni, A, Camerini, S, Crescenzi, M, Lisa, A, Biamonti, G, and Montecucco, A. Phosphorylation of SRSF1 is modulated by replicational stress. Nucleic Acids Res 40:1106-1117, 2012.

Delunardo, F, Scalzi, V, Capozzi, A, Camerini, S, Misasi, R, Pierdominici, M, Pendolino, M, Crescenzi, M, Sorice, M, Valesini, G, Ortona, E, and Alessandri, C. Streptococcal-vimentin cross-reactive antibodies induce microvascular cardiac endothelial proinflammatory phenotype in rheumatic heart disease. Clin Exp Immunol 173:419-429, 2013.

Mallozzi, C, D'Amore, C, Camerini, S, Macchia, G, Crescenzi, M, Petrucci, TC, and Di Stasi, AM. Phosphorylation and nitration of tyrosine residues affect functional properties of Synaptophysin and Dynamin I, two proteins involved in exo-endocytosis of synaptic vesicles. Biochim Biophys Acta 1833:110-121, 2013.

Siepi, F, Gatti, V, Camerini, S, Crescenzi, M, and Soddu, S. HIPK2 catalytic activity and subcellular localization are regulated by activation-loop Y354 autophosphorylation. Biochim Biophys Acta 1833:1443-1453, 2013.

Simonelli, V, Camerini, S, Mazzei, F, Van Loon, B, Allione, A, D'Errico, M, Barone, F, Minoprio, A, Ricceri, F, Guarrera, S, Russo, A, Dalhus, B, Crescenzi, M, Hubscher, U, Bjoras, M, Matullo, G, and Dogliotti, E. Genotype-phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies. Free radical biology & medicine 63:401-409, 2013.

Yamamoto, DL, Vitiello, C, Zhang, J, Gokhin, DS, Castaldi, A, Coulis, G, Piaser, F, Filomena, MC, Eggenhuizen, PJ, Kunderfranco, P, Camerini, S, Takano, K, Endo, T, Crescenzi, M, Luther, PK, Lieber, RL, Chen, J, and Bang, ML. The nebulin SH3 domain is dispensable for normal skeletal muscle structure but is required for effective active load bearing in mouse. J Cell Sci 126:5477-5489, 2013.

Brignone, MS, Lanciotti, A, Visentin, S, De Nuccio, C, Molinari, P, Camerini, S, Diociaiuti, M, Petrini, S, Minnone, G, Crescenzi, M, Laudiero, LB, Bertini, E, Petrucci, TC, and Ambrosini, E. Megalencephalic leukoencephalopathy with subcortical cysts protein-1 modulates endosomal pH and protein trafficking in astrocytes: relevance to MLC disease pathogenesis. Neurobiol Dis 66:1-18, 2014.

De Nicola, F, Catena, V, Rinaldo, C, Bruno, T, Iezzi, S, Sorino, C, Desantis, A, Camerini, S, Crescenzi, M, Floridi, A, Passananti, C, Soddu, S, and Fanciulli, M. HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation. Cell death & disease 5:e1414, 2014.

Metere, A, Iorio, E, Scorza, G, Camerini, S, Casella, M, Crescenzi, M, Minetti, M, and Pietraforte, D. Carbon monoxide signaling in human red blood cells: evidence for pentose phosphate pathway activation and protein deglutathionylation. Antioxid Redox Signal 20:403-416, 2014.

Motta, M, Camerini, S, Tatti, M, Casella, M, Torreri, P, Crescenzi, M, Tartaglia, M, and Salvioli, R. Gaucher disease due to saposin C deficiency is an inherited lysosomal disease caused by rapidly degraded mutant proteins. Human molecular genetics 23:5814-5826, 2014.

Barbati, C, Alessandri, C, Vomero, M, Vona, R, Colasanti, T, Vacirca, D, Camerini, S, Crescenzi, M, Pendolino, M, Truglia, S, Conti, F, Garofalo, T, Sorice, M, Pierdominici, M, Valesini, G, Malorni, W, and Ortona, E. Autoantibodies specific to D4GDI modulate Rho GTPase mediated cytoskeleton remodeling and induce autophagy in T lymphocytes. J Autoimmun 58:78-89, 2015.

Cherubini, F, Serio, D, Guccini, I, Fortuni, S, Arcuri, G, Condo, I, Rufini, A, Moiz, S, Camerini, S, Crescenzi, M, Testi, R, and Malisan, F. Src inhibitors modulate frataxin protein levels. Human molecular genetics 24:4296-4305, 2015.

Camerini, S, Montepeloso, E, Casella, M, Crescenzi, M, Marianella, RM, and Fuselli, F. Mass spectrometry detection of fraudulent use of cow whey in water buffalo, sheep, or goat Italian ricotta cheese. Food Chem 197 Pt B:1240-1248, 2016.

Burla, R, Carcuro, M, Torre, ML, Fratini, F, Crescenzi, M, D'Apice, MR, Spitalieri, P, Raffa, GD, Astrologo, L, Lattanzi, G, Cundari, E, Raimondo, D, Biroccio, A, Gatti, M, and Saggio, I. The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence. Open Biol 6, 2016.

Delunardo, F, Soldati, D, Bellisario, V, Berry, A, Camerini, S, Crescenzi, M, Alessandri, C, Conti, F, Ceccarelli, F, Francia, A, Valesini, G, Cirulli, F, Siracusano, A, Siracusano, A, Niolu, C, Alex Rubino, I, Ortona, E, and Margutti, P. Anti-GAPDH Autoantibodies as a Pathogenic Determinant and Potential Biomarker of Neuropsychiatric Diseases. Arthritis Rheumatol 68:2708-2716, 2016.

Emanuele, M, Esposito, A, Camerini, S, Antonucci, F, Ferrara, S, Seghezza, S, Catelani, T, Crescenzi, M, Marotta, R, Canale, C, Matteoli, M, Menna, E, and Chieregatti, E. Exogenous Alpha-Synuclein Alters Pre- and Post-Synaptic Activity by Fragmenting Lipid Rafts. EBioMedicine 7:191-204, 2016.

 

 

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